Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs

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136.pdf (1.46 MB)

Date

2023

Document type

Artículo

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Investigación
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Authors

Espinosa Saez, Roger., Robledo, Sara M., Pineda, Tatiana, Murillo, Javier, Zúñiga, César, Yáñez Osses, Osvaldo Andrés., Cantero López, Plinio., Sáez Vega, Alex., Guzmán Teran, Camilo.

Faculty

Facultad de Ingeniería y Negocios

Publisher

Nature Research

URI

http://repositorio.udla.cl/xmlui/handle/udla/1333, https://www.nature.com/srep/

DOI

10.1038/s41598-023-43805-4

Citation

Scientific Reports, 13(1), 16 p.

Extent

16 páginas
1.455Mb

Abstract

In this study, six analogs of 2-arylquinoline were synthesized and evaluated for their in vitro and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and druggab...

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