Discovery of New 2-Phenylamino-3-acyl-1,4-naphthoquinones as Inhibitors of Cancer Cells Proliferation: Searching for Intra-Cellular Targets Playing a Role in Cancer Cells Survival

Thumbnail Image

Files

219.pdf (3.51 MB)

Date

2023

Document type

Artículo

Collections

Investigación
Total downloads0
Total views1
Bibliographic managers

Authors

Benites, Julio, Valderrama, Jaime A., Contreras, Álvaro, Enríquez, Cinthya, Pino Ríos, Ricardo., Yáñez Osses, Osvaldo Andrés., Buc Calderon, Pedro.

Faculty

Facultad de Ingeniería y Negocios

Publisher

MDPI

URI

http://repositorio.udla.cl/xmlui/handle/udla/1344, https://www.mdpi.com/journal/molecules

DOI

10.3390/molecules28114323

Keywords

Antiproliferative activity, Molecular descriptors, Molecular docking, mTOR

Citation

Molecules, 28(11), 23 p.

Extent

23 páginas
3.510Mb

Abstract

A series of 2-phenylamino-3-acyl-1,4-naphtoquinones were evaluated regarding their in vitro antiproliferative activities using DU-145, MCF-7 and T24 cancer cells. Such activities were discussed in ter...

Endorsement

Review

Supplemented By

Referenced By

Usage statistics
01345
Aug 25Sep 25Oct 25Nov 25Dec 25Jan 26Feb 26