Discovery of New 2-Phenylamino-3-acyl-1,4-naphthoquinones as Inhibitors of Cancer Cells Proliferation: Searching for Intra-Cellular Targets Playing a Role in Cancer Cells Survival

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Date

2023-05-24

Document type

journal article

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Investigación
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Authors

Benites, Julio, Valderrama, Jaime A., Contreras, Alvaro, Enriquez, Cinthya, Pino-Rios, Ricardo, Yáñez, Osvaldo, Buc Calderon, Pedro

Publisher

MDPI AG

URI

https://repositorio.udla.cl/handle/udla/1344

DOI

https://doi.org/10.3390/molecules28114323

Keywords

cancer cells, quinones, mTOR, antiproliferative activity, molecular descriptors, molecular docking

Citation

Molecules, 28(11), 4323. https://doi.org/10.3390/molecules28114323

Abstract

A series of 2-phenylamino-3-acyl-1,4-naphtoquinones were evaluated regarding their in vitro antiproliferative activities using DU-145, MCF-7 and T24 cancer cells. Such activities were discussed in ter...

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Creative Commons Attribution 4.0 International
Except where otherwised noted, this item's license is described as Creative Commons Attribution 4.0 International
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