Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells

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dc.contributor.affiliationUniversidad de Las Americas - Chile
dc.contributor.affiliationUniversity of Belgrade
dc.contributor.affiliationUniversidad Bernardo O'Higgins
dc.contributor.affiliationUniversidad de Atacama
dc.contributor.affiliationUniversidad San Sebastian
dc.contributor.authorRamirez-Tagle, Rodrigo
dc.contributor.authorAlvarado-Soto, Leonor
dc.contributor.authorSantibanez, Juan F.
dc.contributor.authorEcheverria, Cesar
dc.date.accessioned2024-09-03T19:20:48Z
dc.date.available2024-09-03T19:20:48Z
dc.date.issued2023-08-24
dc.description.abstractRelationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cells
dc.format.mimetypeapplication/pdf
dc.identifier.citationAfinidad, 80(599), 174-179. https://doi.org/10.55815/417980
dc.identifier.doihttps://doi.org/10.55815/417980
dc.identifier.issn2339-9686
dc.identifier.orcidhttps://orcid.org/0000-0003-0694-1808
dc.identifier.orcidhttps://orcid.org/0000-0001-5431-7183
dc.identifier.researcheridL-3519-2017
dc.identifier.researcheridAAH-4994-2019
dc.identifier.researcheridK-7071-2016
dc.identifier.rorhttps://ror.org/02qsmb048
dc.identifier.rorhttps://ror.org/022yres73
dc.identifier.rorhttps://ror.org/0166e9x11
dc.identifier.scopusauthorid23670533200
dc.identifier.scopusauthorid25651555300
dc.identifier.scopusauthorid56544274300
dc.identifier.scopusauthorid26026867200
dc.identifier.urihttps://repositorio.udla.cl/handle/udla/1556
dc.language.isoeng
dc.publisherInstitut Quimic de Sarria
dc.relation.isindexedbyWeb of Science
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.sourceAfinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry
dc.source.urihttps://raco.cat/index.php/afinidad/article/view/417980
dc.subject.oecd11 Ciencias Naturales
dc.subject.oecd21.4 Ciencias Químicas
dc.titleRelationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells
dc.title.alternativeRelacions entre les caracterfstiques estructurals de les curcumines que afecten la proliferacio cellular de les cel-lules de /'hepatocarcinoma]; [Relaciones entre las caracteristicas estructurales de las curcuminas que afectan la proliferacion celular de las celulas de hepatocarcinoma
dc.title.alternativeRelationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells.
dc.typejournal article
dc.type.coarhttp://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.udla.catalogadorCBM
oaire.citation.endPage180
oaire.citation.issue599
oaire.citation.startPage175
oaire.citation.titleAfinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry
oaire.citation.volume80
udla.curacion.controljmvg
udla.oecd.area1 Ciencias Naturales
udla.oecd.subarea1.4 Ciencias Químicas

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