Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model

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2025-09

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journal article

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Authors

Ormazabal, Paulina, Gherardelli, Camila, Pinto, Cristina, Servili, Evrim, Mendez-Orellana, Carolina, Wong, G. William, Contreras-Díaz, Roberto, Cisternas, Pedro, Inestrosa, Nibaldo C.

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American Society for Biochemistry and Molecular Biology Inc.

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https://repositorio.udla.cl/handle/udla/2292

DOI

https://doi.org/10.1016/j.jbc.2025.110607

Keywords

Alzheimer's disease, andrographolide, glucose metabolism, obesity, visceral adipose tissue

Citation

Ormazabal, Paulina; Gherardelli, Camila; Pinto, Cristina; Servili, Evrim; Mendez-Orellana, Carolina; Wong, G. William; Contreras-Díaz, Roberto; Cisternas, Pedro; Inestrosa, Nibaldo C. (2025). Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model. Journal of Biological Chemistry, 301(10), 110607. https://doi.org/10.1016/j.jbc.2025.110607

Abstract

Midlife obesity and high adiposity are recognized as risk factors for Alzheimer's disease (AD), with visceral adipose tissue (VAT) playing a central role due to its endocrine and metabolic activity. D...

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Except where otherwised noted, this item's license is described as Creative Commons Attribution 4.0 International
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