Effectiveness of omega-3 fatty acid supplementation in patients with Alzheimer disease: A systematic review and meta-analysis

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dc.contributor.affiliationUniversity of the Americas
dc.contributor.affiliationUniversity of the Americas
dc.contributor.affiliationHospital San Borja Arriarán
dc.contributor.affiliationUniversity of the Americas
dc.contributor.affiliationUniversidad Gabriela Mistral
dc.contributor.affiliationUniversity of the Americas
dc.contributor.affiliationUniversity of the Americas
dc.contributor.affiliationUniversity of the Americas
dc.contributor.authorAraya-Quintanilla, F.
dc.contributor.authorGutiérrez-Espinoza, H.
dc.contributor.authorSánchez-Montoya, U.
dc.contributor.authorMuñoz-Yañez, M.J.
dc.contributor.authorBaeza-Vergara, A.
dc.contributor.authorPetersen-Yanjarí, M.
dc.contributor.authorFernández-Lecaros, L.
dc.date.accessioned2021-08-06T18:45:20Z
dc.date.available2021-08-06T18:45:20Z
dc.date.issued2020-03
dc.description.abstractAlzheimer disease (AD) is a neurodegenerative disease characterised by progressive dementia associated with global cognitive dysfunction.We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD.To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD.We included only randomised controlled trials (RCTs) from the following databases: Medline, Cochrane Central, Cinahl, and LILACS. An electronic search was also conducted using Google Scholar.Six articles met the eligibility criteria. The risk of bias was assessed following the Cochrane method.There is no consistent evidence to support the effectiveness of omega-3 supplementation in improving cognitive function in AD patients in the short and medium term.
dc.format.mimetypeapplication/pdf
dc.identifier.citationNEUROLOGIA, 35(2), 105-114. https://doi.org/10.1016/j.nrt.2017.07.009
dc.identifier.doihttps://doi.org/10.1016/j.nrleng.2017.07.014
dc.identifier.issn2173-5808
dc.identifier.orcidhttps://orcid.org/0000-0003-1293-4233
dc.identifier.orcidhttps://orcid.org/0000-0002-4650-3426
dc.identifier.orcidhttps://orcid.org/0000-0002-3902-5622
dc.identifier.pmid28986068
dc.identifier.researcheridGutiérrez Espinoza, Héctor Joaquín/S-3596-2017
dc.identifier.researcheridAraya - Quintanilla, Felipe/O-9791-2018
dc.identifier.rorhttps://ror.org/0166e9x11
dc.identifier.rorhttps://ror.org/04qdwp261
dc.identifier.rorhttps://ror.org/05wygq130
dc.identifier.urihttps://repositorio.udla.cl/handle/udla/868
dc.language.isoeng
dc.publisherElsevier BV
dc.relation.isindexedbyWeb of Science
dc.relation.isindexedbyScience Citation Index Expanded (SCI-EXPANDED)
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://www.elsevier.com/tdm/userlicense/1.0/
dc.sourceNeurología (English Edition)
dc.source.urihttps://www.sciencedirect.com/science/article/pii/S2173580820300420
dc.subjectAlzheimer disease
dc.subjectOmega-3 fatty acids
dc.subjectCognitive function
dc.subjectRandomised controlled trial
dc.subjectSystematic review
dc.titleEffectiveness of omega-3 fatty acid supplementation in patients with Alzheimer disease: A systematic review and meta-analysis
dc.typejournal article
dc.type.coarhttp://purl.org/coar/resource_type/c_6501
dc.type.driverinfo:eu-repo/semantics/article
dc.udla.catalogadorJLS
oaire.citation.endPage114
oaire.citation.issue2
oaire.citation.startPage105
oaire.citation.titleNeurología (English Edition)
oaire.citation.volume35
udla.curacion.controljmvg

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