Adipokines at the Metabolic–Brain Interface: Therapeutic Modulation by Antidiabetic Agents and Natural Compounds in Alzheimer’s Disease

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Date

2025-10

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journal article

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Authors

Ormazabal, Paulina, Bastías-Pérez, Marianela, Inestrosa, Nibaldo C., Cisternas, Pedro

Publisher

Multidisciplinary Digital Publishing Institute (MDPI)

URI

https://repositorio.udla.cl/handle/udla/2313

DOI

https://doi.org/10.3390/ph18101527

Keywords

insulin resistance, adipose tissue dysfunction, metabolic inflammation, pharmacological interventions, GLP-1 receptor agonists, metformin, thiazolidinediones, SGLT2 inhibitors, DPP-4 inhibitors, phytochemicals, adiponectin, leptin

Citation

Ormazabal, Paulina; Bastías-Pérez, Marianela; Inestrosa, Nibaldo C.; Cisternas, Pedro (2025). Adipokines at the Metabolic–Brain Interface: Therapeutic Modulation by Antidiabetic Agents and Natural Compounds in Alzheimer’s Disease. Pharmaceuticals, 18(10), 1527. https://doi.org/10.3390/ph18101527

Abstract

The parallel global increase in obesity and Alzheimer’s disease (AD) underscores an urgent public health challenge, with converging evidence indicating that metabolic dysfunction strongly contributes ...

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Creative Commons Attribution 4.0 International
Except where otherwised noted, this item's license is described as Creative Commons Attribution 4.0 International
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