Genome Sequencing Variations in the Octodon degus, an Unconventional Natural Model of Aging and Alzheimer''s Disease

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Date

2022

Document type

Artículo

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Investigación
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Authors

Hurley, Michael J., Urra, Claudio, Garduno, Maximiliano, Bruno, Agostino, Kimbell, Allison, Wilkinson, Brent, Marino Buslje, Cristina., Ezquer, Marcelo, Ezquer, Fernando, Aburto, Pedro F., Poulin, Elie, Vásquez, Rodrigo A., Deacon, Robert, Ávila, Ariel, Altimiras Gonzalez, Francisco Javier., Vanderklish, Peter Whitney, Zampieri, Guido, Angione, Claudio, Constantino, Gabriele, Holmes, Todd C., Coba, Marcelo P., Xu, Xiangmin, Cogram, Patricia

Faculty

Facultad de Ingeniería y Negocios

Publisher

Frontiers Media

URI

http://repositorio.udla.cl/xmlui/handle/udla/1371, https://www.frontiersin.org/journals/aging-neuroscience

DOI

10.3389/fnagi.2022.894994

Keywords

Amyloids, APOE, Lipid droplets, Octodon degus

Citation

Frontiers in Aging Neuroscience, 14,16 p.

Extent

16 páginas
4.355Mb

Abstract

The degu (Octodon degus) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age some degu, but not all individua...

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