In vitro and in silico analysis of galanthine from Zephyranthes carinata as an inhibitor of acetylcholinesterase

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Sierra.2022. In vitro and in silico analysis of galanthine from Zephyranthes carinata as an inhibitor of acetylcholinesterase.pdf (3.21 MB)

Date

2022-06

Document type

journal article

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Investigación
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Authors

Sierra, Karina, de Andrade, Jean Paulo, Tallini, Luciana R., Osorio, Edison H., Yáñez, Osvaldo, Osorio, Manuel Isaias, Oleas, Nora H., García-Beltrán, Olimpo, S. Borges, Warley de, Bastida, Jaume, Osorio, Edison, Cortes, Natalie

Publisher

Elsevier BV

URI

https://repositorio.udla.cl/handle/udla/996

DOI

https://doi.org/10.1016/j.biopha.2022.113016

Keywords

Amaryllidaceae alkaloids, Galanthine, Acetylcholinesterase inhibition, Molecular docking, Molecular dynamics

Citation

Biomedicine and Pharmacotherapy, 150, 113016. https://doi.org/10.1016/j.biopha.2022.113016

Abstract

Zephyranthes carinata Herb., a specie of the Amaryllidoideae subfamily, has been reported to have inhibitory activity against acetylcholinesterase. However, scientific evidence related to their bioact...

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