Colloidal nanomedicines with prolonged release of chloroquine based on interactions with aromatic polymers after mixing two liquids: from in silico simulation of nanoparticle formation to efficient in-bench scale up

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040-Colloidal nanomedicines.pdf (9.33 MB)

Date

2024-02

Document type

journal article

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Investigación
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Authors

Villamizar-Sarmiento, Maria Gabriela, Yáñez, Osvaldo, Flores, Mario E., Alvarez-Acevedo, Gonzalo, Gonzalez-Nilo, Fernando, Guerrero, Juan, Moreno-Villoslada, Ignacio, Oyarzun-Ampuero, Felipe A.

Publisher

Elsevier BV

URI

https://repositorio.udla.cl/handle/udla/1871

DOI

https://doi.org/10.1016/j.molliq.2023.123906

Keywords

Chloroquine, Aromatic-aromatic interactions, Aromatic polyelectrolytes, Nanoparticles, Drug delivery, Prolonged release

Citation

Journal of Molecular Liquids, 395, 123906. https://doi.org/10.1016/j.molliq.2023.123906

Abstract

Nanomedicines containing the aromatic drug chloroquine and the polymer poly(sodium 4-styrenesulfonate) have been theoretically designed and experimentally synthesized following the simple mixture of t...

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