Publication:
Therapeutic challenges in central nervous system viral infections: advancing mesenchymal stem cell-based strategies for treating neuroinflammation and promoting tissue repair

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Date

2025-11

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journal article

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Authors

Carbone-Schellman, Javier, Fontecilla-Escobar, Javiera, Sales-Salinas, Nicolás, Chaparro-Pico, William F., Molina-Berríos, Alfredo, Ruete, María Celeste, González, Pablo A., Machuca, Mayra A., Opazo, Ma. Cecilia, Ezquer, Marcelo E., Duarte, Luisa F.

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Frontiers Media SA

URI

https://repositorio.udla.cl/handle/udla/2172

DOI

https://doi.org/10.3389/fimmu.2025.1677433

Keywords

virus, mesenchymal stem cells, central nervous system (CNS), neuroinflammation, secretome, extracellular vesicle (EV), neurological and neurodegenerative diseases, persistent infections

Citation

Carbone-Schellman, Javier; Fontecilla-Escobar, Javiera; Sales-Salinas, Nicolás; Chaparro-Pico, William F.; Molina-Berríos, Alfredo; Ruete, María Celeste; González, Pablo A.; Machuca, Mayra A.; Opazo, Ma. Cecilia; Ezquer, Marcelo E.; Duarte, Luisa F. (2025). Therapeutic challenges in central nervous system viral infections: advancing mesenchymal stem cell-based strategies for treating neuroinflammation and promoting tissue repair. Frontiers in Immunology, 16, 1677433. https://doi.org/10.3389/fimmu.2025.1677433

Abstract

Although significant progress has been made in medicine and antimicrobial research, viral infections continue to pose a critical global health challenge, particularly when they involve the central ner...

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