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dc.contributor.authorAuthorPascual-Morena, Carlos.
dc.contributor.authorAuthorCavero-Redondo, Iván.
dc.contributor.authorAuthorÁlvarez-Bueno, Celia.
dc.contributor.authorAuthorLucas-Torres, Maribel Lucerón.
dc.contributor.authorAuthorSanabria-Martínez, Gema.
dc.contributor.authorAuthorPoyatos-León, Raquel.
dc.contributor.authorAuthorRodríguez-Martín, Beatriz.
dc.contributor.authorAuthorMartínez-Vizcaíno, Vicente.
dc.date.accessionedDate Accessioned2024-09-03T19:21:36Z
dc.date.availableDate Available2024-09-03T19:21:36Z
dc.date.issuedDate Issued2021
dc.identifier.citationReferencia BibliográficaJournal of Clinical Medicine, 10(16), 18 p.
dc.identifier.issnISSN2077-0383
dc.identifier.uriURIhttp://repositorio.udla.cl/xmlui/handle/udla/1657
dc.identifier.uriURIhttps://www.mdpi.com/journal/jcm
dc.description.abstractAbstractBeing overweight is associated with pregnancy-related disorders such as gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), and excessive maternal weight gain (MWG). Exercise and metformin reduce the risk of these disorders. This network meta-analysis (NMA) aims to compare the effect of metformin and different types of exercise (aerobic, resistance and combined) on the risk of GDM, HDP, and MWG among overweight/obese pregnant women. Medline, EMBASE, Web of Science and Cochrane Library were searched from inception to June 2021. Meta-analyses and NMAs were performed. Sixteen randomized controlled trials were included. In the NMA, aerobic exercise showed an effect on GDM (RR = 0.51, 95% CI = 0.26, 0.97), and metformin a reduction in MWG (MWG = −2.93 kg, 95% CI = −4.98, −0.87). No intervention showed any effect on the reduction of HDP. Our study suggests that aerobic exercise may have the greatest effect in reducing the risk of GDM, and perhaps, the MWG. Strategies should be developed to increase adherence to this type of intervention among overweight women without contraindications. Although metformin could reduce MWG, medicalization of pregnancy in healthy women is not justified with the present results. More research is needed on the effect of the intensity and frequency of exercise sessions and the length of interventions.
dc.format.extentdc.format.extent18 páginas
dc.format.extentdc.format.extent1.528Mb
dc.format.mimetypedc.format.mimetypePDF
dc.language.isoLanguage ISOeng
dc.publisherPublisherMDPI
dc.rightsRightsCreative Commons Attribution License (CC BY)
dc.sourceSourcesJournal of Clinical Medicine
dc.subjectSubjectGestational diabetes mellitus
dc.subjectSubjectNetwork meta-analysis
dc.subjectSubjectOverweight
dc.subjectSubjectSystematic review
dc.subject.lcshdc.subject.lcshEjercicio físico
dc.subject.lcshdc.subject.lcshMetformina
dc.subject.lcshdc.subject.lcshObesidad
dc.subject.lcshdc.subject.lcshEmbarazo
dc.titleTitleExercise versus metformin to improve pregnancy outcomes among overweight pregnant women: A systematic review and network meta-analysis
dc.typeDocument TypeArtículo de revisión
dc.identifier.doidc.identifier.doi10.3390/jcm10163490
dc.facultaddc.facultadFacultad de Salud y Ciencias Sociales


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