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dc.contributor.authorAuthorSepúlveda-Loyola, Walter .
dc.contributor.authorAuthorCarnicero, José A.
dc.contributor.authorAuthorÁlvarez-Bustos, Alejandro.
dc.contributor.authorAuthorSuziane Probst, Vanessa
dc.contributor.authorAuthorGarcía-García, Francisco J.
dc.contributor.authorAuthorRodríguez-Mañas, Leocadio.
dc.date.accessionedDate Accessioned2023-06-12T16:01:42Z
dc.date.availableDate Available2023-06-12T16:01:42Z
dc.date.issuedDate Issued2023
dc.identifier.citationReferencia BibliográficaHeart and Lung, 59, 10 p.
dc.identifier.issnISSN0147-9563
dc.identifier.otherDegree Control Codehttps://doi.org/10.1016/j.hrtlng.2023.01.020
dc.identifier.uriURIhttp://repositorio.udla.cl/xmlui/handle/udla/1162
dc.identifier.uriURIhttps://www.heartandlung.org/article/S0147-9563(23)00020-1/fulltext
dc.description.abstractAbstractBackground The relationship between pulmonary impairment and frailty has rarely been studied in community-dwelling older adults. Objective This study aimed to analyze the association between pulmonary function and frailty (prevalent and incident), identifying the best cut-off points to detect frailty and its association with hospitalization and mortality. Methods A longitudinal observational cohort study with 1188 community-dwelling older adults was taken from the Toledo Study for Healthy Aging. The forced expiratory volume in the first second (FEV1) and the forced vital capacity (FVC) were measured with spirometry. Frailty was evaluated using the Frailty Phenotype and Frailty Trait Scale 5. Associations between pulmonary function and frailty, hospitalization and mortality in a 5-year follow-up and the best cut-off points for FEV1 and FVC were analyzed. Results FEV1 and FVC were associated with frailty prevalence (OR from 0.25 to 0.60), incidence (OR from 0.26 to 0.53), and hospitalization and mortality (HR from 0.35 to 0.85). The cut-off points of pulmonary function identified in this study: FEV1 (≤1.805 L for male and ≤1.165 L for female) and FVC (≤2.385 L for male and ≤1.585 L for female) were associated with incident frailty (OR: 1.71–4.06), hospitalization (HR: 1.03–1.57) and mortality (HR: 2.64–5.17) in individuals with and without respiratory diseases (P < 0.05 for all). Conclusion Pulmonary function was inversely associated with the risk of frailty, hospitalization and mortality in community-dwelling older adults. The cut-off points for FEV1 and FVC to detect frailty were highly associated with hospitalization and mortality in the 5-year follow-up, regardless of the existence of pulmonary diseases.es
dc.format.extentdc.format.extent10 páginas
dc.format.extentdc.format.extent262.6Kb
dc.format.mimetypedc.format.mimetypePDF
dc.languagedc.languageen
dc.relation.ispartofseriesSeriesHeart & Lung
dc.sourceSourcesHeart & Lung
dc.subjectSubjectFrailty syndrome.es
dc.subjectSubjectCut-point.
dc.subjectSubjectOlder adults.
dc.subject.lcshdc.subject.lcshPulmonary function tests.
dc.subject.lcshdc.subject.lcshAging.
dc.subject.lcshdc.subject.lcshOlder people.
dc.titleTitlePulmonary function is associated with frailty, hospitalization and mortality in older people: 5-year follow-upes
dc.typeDocument TypeArtículoes
dc.udla.indexdc.udla.indexSCOPUS
dc.udla.privacidaddc.udla.privacidadDocumento privadoes


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